viral diagnostics advances and applications

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Viral Diagnostics

Author : Robert S. Marks
ISBN : 9789814364430
Genre : Medical
File Size : 77. 45 MB
Format : PDF, ePub
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This book illustrates a variety of challenges that bug hunters try to solve. It is an outstanding collection of the insights and expertise of an interdisciplinary group of researchers from all walks of life: virologists, physicians, immunologists, electrochemists, physicists, computer scientists, biotechnologists, epidemiologists, and molecular biologists, all working at the forefront of diagnostics in fields that cross scientific boundaries. Notwithstanding a dire moment as that of the recent Ebola outbreak in West Africa that saddens us all, we must more than ever peregrinate across oceans, and take the fight to them, as these invisible and exotic but deadly enemies know no barriers and constantly invade our lives. The coming epidemics and killer pandemics require us to continuously innovate in areas of prevention, detection, and therapy. The present volume focuses on creating virus alerts or hand-held detectors to bring to the field during an epidemic, when possible, or tools for the healthcare worker to rapidly diagnose the patient’s ailment. The authors describe the conventional cell cultures and molecular biology methodologies, while introducing state-of-the-art multidisciplinary biosensors. This book is not a manual, set of protocols, or a textbook; it is a glimpse into the advances of virus diagnostic research. Included are a variety of topics that encompass world health issues, local folklore such as associating outbreaks with witchcraft, problems in getting healthcare workers to the outbreak areas, and insights in viral diagnostic pitfalls.

Molecular Diagnostics

Author : Wayne W. Grody
ISBN : 0080919049
Genre : Science
File Size : 27. 53 MB
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Advances in genomic and proteomic profiling of disease have transformed the field of molecular diagnostics, thus leading the way for a major revolution in clinical practice. While the range of tests for disease detection and staging is rapidly expanding, many physicians lack the knowledge required to determine which tests to order and how to interpret results. This handbook provides a complete guide to the use and interpretation of molecular testing in the clinical arena. No other available resource offers this emphasis, comprehensive scope, and practical utility in the clinical setting. * Serves as the definitivereference for molecular pathologists worldwide * Covers a variety of molecular techniques including next generation sequencing, tumor somatic cell genotyping, infectious and genetic disease tecting, and pharmacogenetics * Discusses in the detail issues concerning quality assurance, regulation, ethics, and future directions for the science

Rna Viruses Advances In Research And Application 2012 Edition

Author :
ISBN : 9781481605847
Genre : Medical
File Size : 25. 98 MB
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RNA Viruses—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about RNA Viruses. The editors have built RNA Viruses—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about RNA Viruses in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of RNA Viruses—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Advanced Techniques In Diagnostic Microbiology

Author : Yi-Wei Tang
ISBN : 9781461439707
Genre : Medical
File Size : 65. 20 MB
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In the United States, hospitals annually report over 5 million cases of infectious-disease-related illnesses: clinical microbiology laboratories in these hospitals are engaged in detecting and identifying the pathogenic microorganisms in clinical specimens collected from these patients with suspected infections. Clearly, the timely and accurate detection/identification of these microbial pathogens is critical for patient treatment decisions and outcomes for millions of patients each year. Despite an appreciation that the outcome of an infectious-disease-related illness is directly related to the time required to detect and identify a microbial pathogen, clinical microbiology laboratories in the United States as well as worldwide have long been hampered by traditional culture-based assays, which may require prolonged incubation time for slowly growing microorganisms such as Mycobacterium tuberculosis. Moreover, traditional culture-based assays often require multiple steps with additional time needed for discernment of species and/or detection of antimicrobial resistance. Finally, these traditional, slow multistep culture-based assays are labor-intensive and required skilled clinical microbiologists at the bench. Over the past several decades, advanced molecular techniques in diagnostic microbiology quietly have been revolutionizing the practice of clinical microbiology in the hospital setting. Indeed, molecular diagnostic testing in general and nucleic-acid-based amplification methods in particular have been heralded as diagnostic tools for the new millennium. There is no question that the development of rapid molecular techniques for nucleic acid amplification/characterization combined with automation and user-friendly software has greatly broadened the diagnostic capabilities of the clinical microbiology laboratory. These technical advances in molecular microbiology over the first decade of the 21st Century have profoundly influenced the physical structure of clinical microbiology laboratories as well as their staffing patterns, workflow, and turnaround time. These molecular microbiology advances have also resulted in the need for a revised and updated second edition of Advanced Techniques in Diagnostic Microbiology. This second edition again provides an updated and comprehensive description of the ongoing evolution of molecular methods for the diagnosis of infectious diseases. In addition, many new chapters have been added, including a chapter on the clinical interpretation and relevance of advanced technique results. The second edition, like the first edition, includes both a “techniques” section describing the latest molecular techniques and an “applications” section describing how these advanced molecular techniques are being used in the clinical setting. Finally, the second edition, like the first edition, utilizes a diverse team of authors who have compiled chapters that provide the reader with comprehensive and useable information on advanced molecular microbiology techniques.

Real Time Pcr

Author : Nick A. Saunders
ISBN : 9781908230225
Genre : Science
File Size : 46. 96 MB
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Real-time PCR technology is an established powerful research tool used in many scientific disciplines and is also utilized for mainstream testing in the regulated markets, such as food, veterinary, and human in-vitro diagnostics. This essential manual provides both the novice and experienced user with an invaluable reference to a wide-range of real-time PCR technologies and applications, and it provides an overview of the theory of this increasingly important technique. Renowned international authors present detailed technical insights into the underlying principles, methods, and practice of real-time PCR. The initial chapters cover the important aspects of real-time PCR, including choosing an instrument and probe system, set-up, nucleic acid synthesis, sample extraction controls, and validation and data analysis. Further chapters provide a comprehensive overview of important real-time PCR methodologies, such as quantification, expression analysis, and mutation detection. This is complemented by the final chapters, which address the application of real-time PCR to diagnosis of infectious diseases, biodefense, veterinary science, food authenticity, and molecular haplotyping. This timely and authoritative volume serves both as a basic introduction to real-time PCR and as a source of current trends and applications for those already familiar with the technology. The editors also aim to stimulate readers of all levels to develop their own innovative approaches to real-time PCR. The book will be an essential text for all laboratories using PCR.

Japanese Encephalitis Viruses Advances In Research And Application 2012 Edition

Author :
ISBN : 9781481600651
Genre : Medical
File Size : 22. 74 MB
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Japanese Encephalitis Viruses—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Japanese Encephalitis Viruses in a concise format. The editors have built Japanese Encephalitis Viruses—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Japanese Encephalitis Viruses in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Japanese Encephalitis Viruses—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Viral Structural Proteins Advances In Research And Application 2013 Edition

Author :
ISBN : 9781481681216
Genre : Science
File Size : 42. 32 MB
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Viral Structural Proteins—Advances in Research and Application: 2013 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about ZZZAdditional Research in a compact format. The editors have built Viral Structural Proteins—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Viral Structural Proteins—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

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