neurodegeneration exploring commonalities across diseases

Download Book Neurodegeneration Exploring Commonalities Across Diseases in PDF format. You can Read Online Neurodegeneration Exploring Commonalities Across Diseases here in PDF, EPUB, Mobi or Docx formats.

Neurodegenerative Diseases

Author : Jagan A. Pillai
ISBN : 9780190233563
Genre :
File Size : 37. 91 MB
Format : PDF, ePub, Mobi
Download : 216
Read : 192

Download Now Read Online


As the global population ages the impact of neurodegenerative diseases like Alzheimer's disease and Parkinson's disease are significant forces in shaping human health and quality of life in the 21st century. Insights into understanding these diseases, and knowing how to treat them are major frontiers of scientific research. Neurodegenerative Diseases: Unifying Principles is the result of a conceptual revolution over the last decade in our understanding of neurodegenerative diseases as sharing unifying features. There is an increasing appreciation of the common biological and pathological features across seemingly varied neurodegenerative diseases that entail protein misfolding dysfunction and its consequences over time. Providing an overview of this conceptual change is the main theme for the book. Conventional approach emphasize the differences among neurodegenerative disorders, here Drs. Cummings and Pillai compile the increasingly compelling evidence that these disorders share many features and that insights in one may be rapidly translated into advances in another. The goal is to accelerate understanding by showing linkages among biological, pathological, can clinical aspects of this class of diseases. This collection of 19, inter-related chapters, articulates and broadens our view of the unifying features that initiate and drive disease progression across a variety of neurodegenerative diseases over time. This book will serve as an outstanding sourcebook of insights from experts that have played key roles in this story.

Neurodegeneration

Author : Anthony Schapira
ISBN : 9780470672686
Genre : Medical
File Size : 67. 82 MB
Format : PDF, Mobi
Download : 901
Read : 1194

Download Now Read Online


This book unites the diverse range of complex neurodegenerative diseases into a textbook designed for clinical practice, edited by globally leading authorities on the subject. Presents a clinically oriented guide to the diseases caused by neurodegeneration Templated chapters combine clinical and research information on neurodegenerative diseases beginning with the common elements before treating each disease individually Diseases are grouped by anatomical regions of degeneration and include common disorders such as Parkinson’s Disease, Alzheimer’s Disease, Amyotrophic Lateral Sclerosis/Motor Neuron Disease, and Multiple Sclerosis as well as less common diseases Edited by globally leading authorities on the subject, and written by expert contributing authors

Dementia Research And Care Can Big Data Help

Author : Anderson Geoff
ISBN : 9789264228429
Genre :
File Size : 53. 43 MB
Format : PDF, ePub, Mobi
Download : 897
Read : 1000

Download Now Read Online


This workshop proceedings advances international discussion of the opportunities and challenges, as well as successful strategies, for sharing and linking the massive amounts of population-based health and health care data that are routinely collected.

Neuronal And Vascular Plasticity

Author : Kenneth Maiese
ISBN : 9781461502821
Genre : Medical
File Size : 65. 26 MB
Format : PDF, ePub, Docs
Download : 900
Read : 637

Download Now Read Online


Galen in the 2nd century AD could be considered one of the earliest researchers who attempted to bridge the gap between basic science and clinical medicine. Galen is given initial credit for the recognition that vital organs of the body are exquisitely dependent upon the intact function of the circulatory system. The doctrines of Galenic physiology stated that blood was produced in the liver, flowed to the heart to obtain "vital spirits", and subsequently bathed the brain to gain "animal spirits". The "vital spirits" described by Galen were later disclosed to consist of oxygen. Oxygen was discovered independently by Schiele in Sweden and by Priestly in England. It was named oxygen (acid-former) by Antoine Lavoisier (1743-1794) of France. Lavoisier made significant medical discoveries concerning oxygen's role in respiration. In animal experiments, Lavoisier and others discovered that anoxia could rapidly lead to death. The initial work by these investigators helped provide direction for modern clinical science and the treatment of disease, especially concerning disorders of the nervous system. Remarkably, our understanding of human disease continues to grow at an exponential rate. At times, the accumulation of knowledge of the cellular components of clinical disease exceeds all prior expectations held just a few years ago, such as evidenced by the recent cloning of the human and mouse genomes. Despite theses advances, both biomedical scientists and clinicians sometimes are at a loss to recognize the crucial link between basic science discovery and the development of therapeutic regiments for clinical disease.

Applied Biclustering Methods For Big And High Dimensional Data Using R

Author : Adetayo Kasim
ISBN : 9781482208245
Genre : Mathematics
File Size : 50. 80 MB
Format : PDF, ePub, Docs
Download : 460
Read : 588

Download Now Read Online


Proven Methods for Big Data Analysis As big data has become standard in many application areas, challenges have arisen related to methodology and software development, including how to discover meaningful patterns in the vast amounts of data. Addressing these problems, Applied Biclustering Methods for Big and High-Dimensional Data Using R shows how to apply biclustering methods to find local patterns in a big data matrix. The book presents an overview of data analysis using biclustering methods from a practical point of view. Real case studies in drug discovery, genetics, marketing research, biology, toxicity, and sports illustrate the use of several biclustering methods. References to technical details of the methods are provided for readers who wish to investigate the full theoretical background. All the methods are accompanied with R examples that show how to conduct the analyses. The examples, software, and other materials are available on a supplementary website.

Alzheimer Disease Sourcebook

Author : Karen Bellenir
ISBN : 0780810015
Genre : Health & Fitness
File Size : 38. 7 MB
Format : PDF, ePub, Docs
Download : 776
Read : 605

Download Now Read Online


"Provides basic consumer health information about Alzheimer disease and other dementias, with tips for coping with memory loss and related complications and advice for caregivers. Includes index, glossary of related terms and directory of resources"--Provided by publisher.

Cardioskeletal Myopathies In Children And Young Adults

Author : John Lynn Jefferies
ISBN : 9780128005804
Genre : Medical
File Size : 22. 33 MB
Format : PDF
Download : 153
Read : 469

Download Now Read Online


Cardioskeletal Myopathies in Children and Young Adults focuses on plaques that kill people in their 40’s-50’s and the way they start to form in young adulthood. The Annals of Family Medicine report that approximately half of young adults have at least one cardiovascular disease risk factor (Mar 2010), and an increase in cardiovascular mortality rates in young adults was substantiated in a study at Northwestern Medicine (Nov 2011). Given the increasing recognition of genetic triggers behind all types of cardiovascular disease, and the growing population of young adults with primary or acquired myocardial disease, the need has arisen for a reference that offers a comprehensive approach to the understanding of basic, translational, and clinical aspects of specific muscle diseases while making the link between young adult and adult health. Reveals the link between cardiac muscle disease and skeletal muscle disease Explains how genetics and environmental factors effect muscle function of diverse origins Designates current and novel therapeutic strategies that target both cardiac and skeletal muscle systems

Top Download:

New Books