cholesterol regulation of ion channels and receptors

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Cholesterol Regulation Of Ion Channels And Receptors

Author : Irena Levitan
ISBN : 9781118342305
Genre : Science
File Size : 52. 70 MB
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Examines new research on the role of cholesterol in regulating ion channels and receptors and its effect on health Drawing together and analyzing all the latest research findings, this book explores the role of cholesterol in the regulation of ion channels and receptors, including its pathological effects. It is the first book to comprehensively describe the complex mechanisms by which cholesterol regulates two major classes of membrane proteins. Moreover, it sheds new light on how cholesterol affects essential cellular functions such as the contraction of the heart, propagation of nerve impulses, and regulation of blood pressure and kidney function. Written and edited by leading pioneers in the field, Cholesterol Regulation of Ion Channels and Receptors is divided into three parts: Part I, Cholesterol Regulation of Membrane Properties, introduces the heterogeneity of cholesterol distribution in biological membranes and the physical and biological implications of the formation of cholesterol-rich membrane domains. Part II, Cholesterol Regulation of Ion Channels, examines the mechanisms underlying cholesterol sensitivities of ion channels, including the regulation of ion channels by cholesterol as a boundary lipid. Part III, Cholesterol Regulation of Receptors, explores the latest discoveries concerning how cholesterol regulates distinct types of receptors, including G-protein coupled receptors, LDL and scavenger receptors, and innate immune system receptors. Increased levels of cholesterol represent a major health risk. Understanding cholesterol regulation of ion channels and receptors is essential for facilitating the development of new therapeutic strategies to alleviate the impact of pathological cholesterol conditions. With this book as their guide, readers have access to the most current knowledge in the field.

Vascular Ion Channels In Physiology And Disease

Author : Irena Levitan, PhD
ISBN : 9783319296357
Genre : Medical
File Size : 62. 45 MB
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Ion channels are the major class of membrane proteins responsible for rapid and regulated transport of ions across biological membranes and for the generation and propagation of electrical signals in the brain, heart, and skeletal and vascular tissues. Ion channels are also known to play critical roles in regulation of cell proliferation, insulin secretion and intracellular signaling in a variety of cell types. This book focuses on the roles of ion channels in vascular tissues under normal and pathological conditions. Vascular abnormalities are known to underlie a plethora of severe pathological conditions, such as atherosclerosis, systemic and pulmonary hypertension, coronary or cerebral vasospasm, and diabetes. In addition, misregulated angiogenesis is one of the major contributors to the development of tumors. Therefore, it is clearly imperative to obtain a better understanding of the molecular mechanisms that contribute to vascular disorders. This book will be the first comprehensive assembly of assays to present the studies that have been done during the last decade to elucidate the roles of ion channels in different vascular diseases.

Regulation Of The Acetylcholine Receptor Function By

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File Size : 42. 17 MB
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Medical Biochemistry E Book

Author : John Baynes
ISBN : 9781455745814
Genre : Medical
File Size : 79. 58 MB
Format : PDF, ePub
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Brought to you in a thorough yet accessible manner, the new edition of Medical Biochemistry gives access to all of the latest information on basic and clinically focused genetic and molecular biology. Featuring a team of contributors that includes investigators involved in cutting-edge research as well as experienced clinicians, this updated medical textbook offers a unique combination of both research and practice that's ideal for today's problem-based integrated courses. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Relate biochemistry to everyday practice with the help of Clinical Boxes integrated into the text, and access in-depth coverage of important topics - including recent research in biochemistry - through Advanced Concept Boxes. Test your knowledge and improve retention with Active Learning Boxes at the conclusion of each chapter, and quickly review the most common lab tests performed with convenient Clinical Test Boxes. Effectively study the most updated information in biochemistry with the help of a dynamic, full-color design. Better understand the relationship between science and clinical practice with material organized by organ rather than system. Gain a thorough understanding of biomarkers and their uses with brand-new information on the subject. Access today's most recent research regarding Gene Therapy, Proteomics and Recombinant DNA Techniques, Role of Kidney in Metabolism, and Neurochemistry.

Electrical Diseases Of The Heart

Author : Ihor Gussak
ISBN : 9781447148814
Genre : Medical
File Size : 80. 73 MB
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Electrical Disease of the Heart, 2nd Edition, volume 1, provides a valuable insight to the latest developments in the field of cardiac electrophysiology and clinical electrocardiology. Each chapter includes up-to-date results of studies aimed at providing an understanding of the electrical function of the heart in health and disease, established and evidence-based knowledge of clinical outcomes, areas of controversy, and future trends. This book is highly relevant to a broad audience, ranging from medical and graduate students, to clinicians and scientists.

Berne Levy Physiology Updated Edition

Author : Bruce M. Koeppen
ISBN : 9780323080309
Genre : Medical
File Size : 42. 13 MB
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Berne and Levy Physiology has long been respected for its scientifically rigorous approach and now includes major updates to bring you all of the latest knowledge in the field. Bruce M. Koeppen and Bruce A. Stanton present a honed and shortened edition that emphasizes the core information needed by students of physiology today and features a full-color design and artwork to enhance readability and enrich your comprehension of every concept. With access to the full contents online at Student Consult, this time-honored book delivers an in-depth understanding of physiology more powerfully and effectively than ever before. Describes all of the mechanisms that control and regulate bodily function using a clear and intuitive organ system-based approach. Provides a rich understanding of the body's dynamic processes through key experimental observations and examples. Includes Student Consult access to the complete and searchable contents of the book online, as well as relevant bonus content from other Student Consult titles, an image gallery, 10 physiology animations, and much more. Features updated coverage throughout to expand your understanding of the most current trends in physiology and medicine, including the latest cellular and molecular knowledge. Includes shaded boxes that highlight and explain important clinical and molecular information. Presents new section editors who ensure that you are getting the freshest, most clinically relevant information available today. Summarizes need-to-know information in each chapter with Key Points sections.

Alcohol And The Brain

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ISBN : 0788100327
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File Size : 41. 7 MB
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Covers: liver-brain relations; sever brain dysfunction; advances in neurochemistry; cognitive-processing deficits; alcohol reinforcement, and much more. Illustrated.

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